| Name |
TWIST1
|
| Type |
gene silence
|
| Species |
Homo sapiens
|
| Tissue |
human non-small cell lung cancer cell lines
|
| Experiment Method |
Western Blotting
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
In the current study, we examine the role of TWIST1 in oncogene-driven human NSCLCs. Silencing of TWIST1 in KRAS-mutant human NSCLC cell lines resulted in dramatic growth inhibition and either activation of a latent oncogene-induced senescence program or,
|
| Regulation Gene |
NA
|
| Year |
2013
|
| Pubmed ID |
23364532
|
| Title |
Inhibition of TWIST2 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer
|
| Drug |
NA
|
| Disease |
non-small cell lung cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|