| Name |
ARC
|
| Type |
histone modification
|
| Species |
Mus musculus
|
| Tissue |
brain
|
| Experiment Method |
qRT-pCR, Western blot, ChIP
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
While the binding of HDAC2 was higher, H3K9 and H3K14 acetylation level was lower at the promoter of these genes in old as compared to young and adult mice.
|
| Regulation Gene |
Arc
|
| Year |
2018
|
| Pubmed ID |
28364391
|
| Title |
Histone Deacetylase 2 Inhibition Attenuates Downregulation of Hippocampal Plasticity Gene Expression during Aging.
|
| Drug |
0
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|