| Name |
B-50
|
| Type |
histone modification
|
| Species |
Mus musculus
|
| Tissue |
various brain areas in aging Wistar rats
|
| Experiment Method |
Protein Kinase C Assay;;Northern and In Situ Hybridization;Western Blot Analysis
|
| Up/Down |
Up
|
| Pro/Anti |
NA
|
| Funtion Description |
In hippocampal membranes, B-50 phosphorylation was increased in aged rats. PKC translocation was impaired in aged rats in both the cortex and the hippocampus. PKC alpha and beta mRNA decreased in the cortex between 3 and 8 months with no further decline i
|
| Regulation Gene |
NA
|
| Year |
1995
|
| Pubmed ID |
7777132
|
| Title |
Protein kinase C activity, translocation, and conventional isoforms in aging rat brain
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|