A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Bdnf
Type histone modification
Species Rat Rattus
Tissue Brain
Experiment Method ChIP;Western Blotting;qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Here, we found that baseline resting levels for tri-methylation of histone H3 at lysine 4 (H3K4me3) and acetylation of histone H3 at lysine 9 and 14 (H3K9,K14ac) were altered in the aged hippocampus as compared to levels in the hippocampus of young adult
Regulation Gene Bdnf
Year 2015
Pubmed ID 25836028
Title Environmental Enrichment Reverses Histone Methylation Changes in the Aged Hippocampus and Restores Age-Related Memory Deficits
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA