A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name BECN1
Type histone modification
Species Mus musculus
Tissue osteo
Experiment Method PCR,ChIP
Up/Down differential expression
Pro/Anti NA
Funtion Description knocking down of Klf2 increased the levels of histone activation marks H3K9 and H4K8 acetylation in the promoter region of Becn1; and overexpression of Klf2 decreased the levels of H4K8 and H3K9 acetylation.
Regulation Gene KLF2,BECN1
Year 2019
Pubmed ID 30894058
Title KLF2 (kruppel like factor 2 [lung]) regulates osteoclastogenesis by modulating autophagy.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA