A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name bmi1
Type histone modification
Species Homo sapiens
Tissue islets
Experiment Method RT-PCR
Up/Down differential expression
Pro/Anti Anti
Funtion Description PcG and TrxG proteins impart a combinatorial code of histone modifications on the Ink4a/Arf locus to control beta-cell proliferation during aging and regeneration.
Regulation Gene Ink4a/Arf
Year 2009
Pubmed ID 19390085
Title Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA