| Name |
CARM1
|
| Type |
histone modification
|
| Species |
Mus musculus
|
| Tissue |
lung
|
| Experiment Method |
PCR, Western blot, Immunofluorescence
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
We further demonstrated that CARM1 haploinsufficiency impairs transdifferentiation and wound healing (32.18 0.9512% versus 8.769 1.967%; P < 0.001) of alveolar epithelial cells. Overall, these results reveal a novel function of CARM1 in regulating e
|
| Regulation Gene |
sirtuin1, p16, p21
|
| Year |
2015
|
| Pubmed ID |
25906418
|
| Title |
Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation.Coactivator-Associated Arginine Methyltransferase-1 Function in Alveolar Epithelial Senescence and Elastase-Induced Emphysema Susceptibility.
|
| Drug |
0
|
| Disease |
Chronic obstructive pulmonary disease
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|