A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CBP
Type histone modification
Species Mus musculus
Tissue The tissues of kidney,heart, liver, brain, muscle (quadriceps femurs), lung,spleen, and testes
Experiment Method Immunoprecipitation; Northern Blot
Up/Down Up
Pro/Anti Pro
Funtion Description HAT activities of p300 and CBP are relatively stable with advancing age in most examined tissues, but in liver, muscle, and testes, the activities are attenuated with aging; and that HAT activities of p300 and CBP are high in the brain and liver of E14 fe
Regulation Gene NA
Year 2002
Pubmed ID 11867645
Title Histone Acetyltransferase Activities of cAMP-Regulated Enhancer-Binding Protein and p300 in Tissues of Fetal, Young, and Old Mice
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA