| Name |
cbx7
|
| Type |
histone modification
|
| Species |
Mus musculus
|
| Tissue |
mammary glands
|
| Experiment Method |
RT-PCR, Immunofluorescence
|
| Up/Down |
Up
|
| Pro/Anti |
Anti
|
| Funtion Description |
we have identified and characterized a novel MAPK-mediated phosphorylation site on Cbx7 and propose that mitogen signaling to the chromatin template regulates PRC1 function.Cbx7T118ph Enhances p16 Repression in Senescence.
|
| Regulation Gene |
Cbx7, p16, PRC1
|
| Year |
2013
|
| Pubmed ID |
24194518
|
| Title |
Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7.
|
| Drug |
EGF
|
| Disease |
mammary cancer
|
| Environment Factors |
null
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|