| Name |
CDKN2A
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
cholangiocyte
|
| Experiment Method |
qRT-pCR, Western blot, ChIP
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Chromatin immunoprecipitation-PCR detected increased ETS1 and histone 3 lysine 4 trimethylation (H3K4Me3) at the CDKN2A promoter following LPS-induced senescence.
|
| Regulation Gene |
CDKN2A
|
| Year |
2017
|
| Pubmed ID |
28184004
|
| Title |
ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A*.
|
| Drug |
0
|
| Disease |
Primary sclerosing cholangitis
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|