| Name |
APOE E4
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
human brain
|
| Experiment Method |
MRI;TBSS image processing and atlas-based ROI analyses
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
The E4 allelic variant of the Apolipoprotein E gene (APOE E4) is the best-established genetic risk factor for late-onset Alzheimer's disease (AD).These findings support previous evidence in monocentric studies indicating a modulatory role of APOE 4 allele
|
| Regulation Gene |
NA
|
| Year |
2017
|
| Pubmed ID |
28596117
|
| Title |
Disrupted white matter structural networks in healthy older adult APOE E4 carriers - An international multicenter DTI study.
|
| Drug |
NA
|
| Disease |
Alzheimer's disease
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|