A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name chromosome 4q35.2
Type histone modification
Species Homo sapiens
Tissue Normal human skin fibroblasts
Experiment Method ChIP,qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description In the latter, acetylation patterns are compared in human skin fibroblast chromatin from donors of various ages. Two sites are reported at which observed histone H4 acetylation differences suggest decreasing acetylation over time. The sites, located in ch
Regulation Gene NA
Year 2004
Pubmed ID 15699521
Title Semirandom sampling to detect differentiation-related and age-related epigenome remodeling
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA