Details
| Name | C-MYC |
| Type | histone modification |
| Species | Homo sapiens |
| Tissue | osteogenic sarcomas cellline;lymphoma derived cell lines |
| Experiment Method | qPCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | The suppression of the c-Myc (MYC) oncogene induces cellular senescence in diverse tumor types including lymphoma, osteosarcoma, and hepatocellular carcinoma. MYC inactivation was associated with prototypical markers of senescence, including acidic B-gal |
| Regulation Gene | MYC |
| Year | 2007 |
| Pubmed ID | 17664422 |
| Title | Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation |
| Drug | NA |
| Disease | lymphoma;osteosarcoma |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |