A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DNMT3B
Type histone modification
Species Rattus norvegicus
Tissue Brains
Experiment Method Global Histone H4 Acetylation Assay Kit,Histone Methyltransferase Activity/Inhibition (H3K27) and DNMT1, DNMT3b Assay Kits
Up/Down NA
Pro/Anti NA
Funtion Description The daily exercise protocol induced an increased in histone H4 acetylation levels in prefrontal cortices of 21-months-old rats, without any effects in young adult group. DNMT3b levels were increased in aged cortices of animals submitted to single session
Regulation Gene H3K27;DNMT1;DNMT3b;H4 acetylation
Year 2016
Pubmed ID 27418438
Title Treadmill exercise induces age and protocol-dependent epigenetic changes in prefrontal cortex of Wistar rats.
Drug NA
Disease NA
Environment Factors Treadmill exercise
Circulating NA
Variant NA
High-throughput NA