| Name |
EC-SOD
|
| Type |
histone modification
|
| Species |
Mus musculus
|
| Tissue |
lung fibroblasts
|
| Experiment Method |
qRT-PCR, ChIP, Western blot,
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
repression of EC-SOD expression was associated with deacetylation of lysine 9 on histone H3 and lysines 5, 8, 12 and 16 on histone H4 located at the gene promoter. Interestingly, the repressive tri-methylation of lysine 27 on histone H3 was elevated in ol
|
| Regulation Gene |
EC-SOD
|
| Year |
2017
|
| Pubmed ID |
28757400
|
| Title |
Epigenetic regulation of EC-SOD expression in aging lung fibroblasts: Role of histone acetylation.
|
| Drug |
0
|
| Disease |
lung disorders
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|