A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name EED
Type histone modification
Species Homo sapiens
Tissue Human hematopoietic stem and progenitor cells
Experiment Method RNAi;ChIP;Western Blotting;qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Even though EED is expressed at comparable amounts in neonatal and adult multipotent HSPCs, early adult lineage committed progenitors of the lymphomyeloid (LM) and erythromyeloid lineages expressed higher EED amounts than neonatal HPCs. We demonstrate tha
Regulation Gene EED
Year 2015
Pubmed ID 25961873
Title Age-Related Increase of EED Expression in Early Hematopoietic Progenitor Cells is Associated with Global Increase of the Histone Modification H3K27me3
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA