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Details


Name FOXO1
Type histone modification
Species Caenorhabditis elegans
Tissue HeLa cells
Experiment Method qRT-PCR, ChIP
Up/Down Up
Pro/Anti Anti
Funtion Description Tip60 is recruited to the promoter regions of the foxo1 gene, where it increases H4K16 acetylation levels. Our results thus identify the evolutionarily conserved role of the MYST family acetyltransferase as a key epigenetic regulator of DAF-16/FOXO transc
Regulation Gene foxo1
Year 2017
Pubmed ID 28794203
Title The MYST family histone acetyltransferase complex regulates stress resistance and longevity through transcriptional control of DAF-16/FOXO transcription factors.
Drug 0
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA