A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Glu4Tyr1
Type histone modification
Species Mus musculus
Tissue rat skeletal muscle and liver
Experiment Method Receptor Autophosphorylation;Exogenous Substrate Phosphorylation;Phosphoamino Acid Analysis
Up/Down Down
Pro/Anti NA
Funtion Description Basal and insulin-stimulated autophosphorylation of liver insulin receptor and its kinase activities toward histone 2b and poly(Glu4Tyr1) did not alter with aging. On the other hand, the muscle insulin receptor showed different results. Insulin-stimulated
Regulation Gene NA
Year 1990
Pubmed ID 2164787
Title Changes in insulin receptor kinase with aging in rat skeletal muscle and liver
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA