| Name |
GSTM3 promoter
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
Human lens epithelial (HLE) cell lines, SRA01/04 and HLEB3
|
| Experiment Method |
quantificational real-time PCR, Western blot, bisulfite-sequencing PCR, pyrosequencing, and chromatin immunoprecipitation assay
|
| Up/Down |
Up
|
| Pro/Anti |
NA
|
| Funtion Description |
Expression of GSTM3 might be regulated by epigenetic changes in lens tissue. Hypermethylation in GSTM3 promoter and altered histone modification might have a role in the ARC formation. The results provided a potential strategy of ARC management by manipul
|
| Regulation Gene |
GSTM3
|
| Year |
2016
|
| Pubmed ID |
27607418
|
| Title |
Relationship Between the Altered Expression and Epigenetics of GSTM3 and Age-Related Cataract.
|
| Drug |
NA
|
| Disease |
ARC
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|