Details
| Name | H2AX |
| Type | histone modification |
| Species | Homo sapiens |
| Tissue | fibroblasts |
| Experiment Method | Western Blotting |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | We show that the incidence of endogenous gamma-H2AX foci increases with age. Fibroblasts taken from patients with Werner syndrome, a disorder associated with premature aging, genomic instability and increased incidence of cancer, exhibited considerably h |
| Regulation Gene | H2AX |
| Year | 2007 |
| Pubmed ID | 18005250 |
| Title | Delayed kinetics of DNA double-strand break processing in normal and pathological aging |
| Drug | NA |
| Disease | Werner syndrome |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |