Details
| Name | ARF |
| Type | gene |
| Species | Homo sapiens |
| Tissue | WI-38 human fibroblasts |
| Experiment Method | Western Blotting;qPCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Replicatively senescent human fibroblasts overexpressed p14(ARF), and ectopic expression of p14(ARF) in presenescent cells induced a phenotype similar to that induced by E2F1. Consistent with a critical role for p14(ARF), cells with compromised p53 functi |
| Regulation Gene | NA |
| Year | 2000 |
| Pubmed ID | 10594030 |
| Title | Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor. |
| Drug | NA |
| Disease | tumor |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |