| Name |
H2AX
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
human neuroblastoma cells
|
| Experiment Method |
qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
We demonstrate that telomere dysfunction induced by adenovirus-mediated expression of dominant-negative TRF2 (DN-TRF2) triggers a DNA damage response involving the formation of nuclear foci containing phosphorylated histone H2AX and activated ATM in each
|
| Regulation Gene |
H2AX
|
| Year |
2006
|
| Pubmed ID |
16539655
|
| Title |
TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|