A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name H2AX
Type histone modification
Species Homo sapiens
Tissue human cell line T19
Experiment Method ChIP,qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description Here we show that senescent human fibroblasts display molecular markers characteristic of cells bearing DNA double-strand breaks. These markers include nuclear foci of phosphorylated histone H2AX and their co-localization with DNA repair and DNA damage ch
Regulation Gene H2AX
Year 2003
Pubmed ID 14608368
Title A DNA damage checkpoint response in telomere-initiated senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA