A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name H3K79me3
Type histone modification
Species Mus musculus
Tissue brain
Experiment Method PCR
Up/Down Down
Pro/Anti Pro
Funtion Description histone methylations in brain tissues, including H3K27me3, H3R2me2, H3K79me3 and H4K20me2 tend to disappear with age but can be partially restored by both DR and rapamycin treatment.However, both DR and rapamycin treatment also have a significant impact
Regulation Gene NA
Year 2015
Pubmed ID 26021816
Title Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain.
Drug rapamycin
Disease Alzheimer's disease
Environment Factors diet
Circulating NA
Variant NA
High-throughput NA