A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name H3K9
Type histone modification
Species Mus musculus
Tissue NA
Experiment Method RT-PCR
Up/Down differential expression
Pro/Anti Pro
Funtion Description SIRT6 attenuates NF-kappaB signaling via H3K9 deacetylation at chromatin, and hyperactive NF-kappaB signaling may contribute to premature and normal aging.
Regulation Gene SIRT6
Year 2009
Pubmed ID 19135889
Title SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA