A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name HAT
Type histone modification
Species Mus musculus
Tissue embryos
Experiment Method Western blotting,immunohistochemistry,RT-PCR,immunoprecipitation,ChIP,
Up/Down Up
Pro/Anti NA
Funtion Description activation of IGF1R/CaMKIV/HAT/BDNF signaling by gestational environment enrichment may serve as a promising strategy to delay AD progression.
Regulation Gene IGF1,IGF1R,BDNF,HAT
Year 2019
Pubmed ID 30867903
Title Enriched gestation activates the IGF pathway to evoke embryo-adult benefits to prevent Alzheimer's disease.
Drug NA
Disease Alzheimer's disease
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA