Details
| Name | HDAC |
| Type | histone modification |
| Species | Mus musculus |
| Tissue | brain |
| Experiment Method | qRT-PCR, Western blot |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | Senescence-accelerated-prone mice (SAMP8) relative to senescence-accelerated-resistant mice (SAMR1) exhibit signs of hastened senescence and can be used as a model for the study of aging. SAMP8 neurospheres lack self-renewal and enter p53-dependent se |
| Regulation Gene | p19 |
| Year | 2015 |
| Pubmed ID | 25728253 |
| Title | Regulation of the p19(Arf)/p53 pathway by histone acetylation underlies neural stem cell behavior in senescence-prone SAMP8 mice. |
| Drug | 0 |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |