Details
| Name | Arg-II |
| Type | gene |
| Species | Mus musculus |
| Tissue | heart and dorsal skin tissues |
| Experiment Method | qRT-PCR;Immunoblotting |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Genetic disruption of Arg-II in mouse extends lifespan predominantly in females, which relates to inhibition of S6K1, p66Shc, and p16INK4a. Thus, Arg-II may represent a promising target to decelerate aging process and extend lifespan as well as to treat a |
| Regulation Gene | NA |
| Year | 2017 |
| Pubmed ID | 28943853 |
| Title | Arginase-II Deficiency Extends Lifespan in Mice. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |