A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name HDAC2
Type histone modification
Species Mus musculus
Tissue lung
Experiment Method PCR
Up/Down differential expression
Pro/Anti Pro
Funtion Description HDAC2 is a key player regulating CS-induced DNA damage, inflammatory response, and cellular senescence leading to COPD/emphysema.
Regulation Gene HDAC2
Year 2018
Pubmed ID 29630406
Title Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema.
Drug NA
Disease Chronic obstructive pulmonary disease/emphysema
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA