Details
| Name | Hdac3 Phosphorylation |
| Type | histone modification |
| Species | Mus musculus |
| Tissue | Bone marrow |
| Experiment Method | Western Blotting;qPCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | Phosphorylation of S424 in Hdac3, a posttranslational mark necessary for deacetylase activity, was suppressed in osseous cells from old mice. Thus, concurrent declines in transcription and phosphorylation combine to suppress Hdac3 activity in aging bone, |
| Regulation Gene | Hdac3 |
| Year | 2016 |
| Pubmed ID | 26211746 |
| Title | Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |