| Name |
HDAC9c
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
osteoblasts and adipocytes
|
| Experiment Method |
Alizarin Red S and Oil Red O Staining,Real-time RT-PCR,Western Blot Analysis
|
| Up/Down |
Down
|
| Pro/Anti |
NA
|
| Funtion Description |
Our findings indicated that a decline in HDAC9c expression over time was accompanied by increased EZH2 expression and suggested that a therapeutic intervention for age-associated osteoporosis and obesity may be feasible by targeting the EZH2-HDAC9c axis.
|
| Regulation Gene |
HDAC9c
|
| Year |
2016
|
| Pubmed ID |
27250566
|
| Title |
Enhancer of Zeste Homolog 2 and Histone Deacetylase 9c Regulate Age-Dependent Mesenchymal Stem Cell Differentiation into Osteoblasts and Adipocytes.
|
| Drug |
NA
|
| Disease |
osteoporosis and obesity
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|