| Name |
HDACs
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
human foreskin
|
| Experiment Method |
Northern blot;SourceQ chromatography;Immunoblot analysis
|
| Up/Down |
Down
|
| Pro/Anti |
NA
|
| Funtion Description |
We found that the overall acetylation pattern of histones does not vary detectably with replicative senescence.We found a significant decrease in the abundance of HDAC-1 in senescent cells. Biochemical analysis of deacetylase activities in extracts from o
|
| Regulation Gene |
NA
|
| Year |
2001
|
| Pubmed ID |
11418121
|
| Title |
Histone deacetylases in replicative senescence: evidence for a senescence-specific form of HDAC-2.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|