| Name |
HMGA2
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
NA
|
| Experiment Method |
qRT-PCR, Flow cytometry assay, Western blot, Immunofluorescence
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Variable DNA compaction observed during senescence is explained in part by cell-type specific regulation of H4 deacetylation and HMGA1/2 expression. Deacetylation of H4-K16Ac during senescence may explain reported decreases in this mark during mammalia
|
| Regulation Gene |
HMGA1/2
|
| Year |
2013
|
| Pubmed ID |
22932127
|
| Title |
Deacetylation of H4-K16Ac and heterochromatin assembly in senescence.
|
| Drug |
Trichostatin A (TSA)
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|