A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name INK4a
Type histone modification
Species Rat Rattus
Tissue liver
Experiment Method PCR,ChIP
Up/Down Down
Pro/Anti NA
Funtion Description HF diet regulated cellular senescence marker p16(INK4a) through chromatin modifications, which may promote hepatic fat accumulation and steatosis.
Regulation Gene INK4a
Year 2018
Pubmed ID 29564021
Title High-fat diet modifies expression of hepatic cellular senescence gene p16(INK4a) through chromatin modifications in adult male rats.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA