Details
| Name | JMJD3 |
| Type | histone modification |
| Species | Mus musculus |
| Tissue | brain |
| Experiment Method | PCR, ChiP, Cell proliferation assay |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Moreover, we showed that the Jmjd3 level was lower in the midbrain of aged mice, which was accompanied by an elevated level of H3K27me3 and an increased ratio of M1 to M2 markers, suggesting that aging is an important factor in switching the microglia |
| Regulation Gene | Jmjd3 |
| Year | 2014 |
| Pubmed ID | 24212761 |
| Title | Jmjd3 is essential for the epigenetic modulation of microglia phenotypes in the immune pathogenesis of Parkinson's disease. |
| Drug | 0 |
| Disease | Parkinson's disease |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |