A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name JMJD3
Type histone modification
Species Mus musculus
Tissue embryo
Experiment Method RT-qPCR
Up/Down Down
Pro/Anti NA
Funtion Description The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence.
Regulation Gene INK4A-ARF
Year 2009
Pubmed ID 19451217
Title The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA