Details
| Name | Jun |
| Type | histone modification |
| Species | Homo sapiens |
| Tissue | human fibroblasts |
| Experiment Method | lar RNA was purified by guanidine-thiocyanate extraction;RT-PCR |
| Up/Down | Down |
| Pro/Anti | NA |
| Funtion Description | We have monitored mRNA expression levels of c-fos, c-jun, JunB, c-myc, p53, H-ras, and histone H4 during the replicative senescence of human fibroblasts. The earliest and the largest changes in gene expression occurred in c-fos and junB at mid-senescence |
| Regulation Gene | NA |
| Year | 1992 |
| Pubmed ID | 1511730 |
| Title | An altered repertoire of fos/jun (AP-1) at the onset of replicative senescence |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |