A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name KAT6A
Type histone modification
Species Homo sapiens
Tissue NA
Experiment Method RT-qPCR
Up/Down differential expression
Pro/Anti Anti
Funtion Description KAT6A suppresses cellular senescence through the regulation of suppressors of the CDKN2A locus9,10, a function that requires its KAT activity10.
Regulation Gene CDKN2A
Year 2018
Pubmed ID 30069049
Title Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE108244