Details
| Name | KDM6B |
| Type | histone modification |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | qPCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | 1,25-dihydroxyvitamin D3 (the active form of vitamin D3) induces senescence of glioma cells and increases the expression of senescence markers, INK4A and cyclin-dependent kinase inhibitor 1A (CDKN1A). |
| Regulation Gene | CDKN1A,INK4A |
| Year | 2019 |
| Pubmed ID | 30825201 |
| Title | Histone demethylase KDM6B regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells. |
| Drug | 1,25-dihydroxyvitamin D3 |
| Disease | glioma |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |