A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name KMT1
Type histone modification
Species Homo sapiens
Tissue NA
Experiment Method qPCR,PCR,ChIP-seq
Up/Down differential expression
Pro/Anti Anti
Funtion Description the loss of EHMTs induces many hallmarks of aging including global reduction of H3K27methyl marks and altered nuclear morphology.
Regulation Gene LMNB1
Year 2019
Pubmed ID 30858340
Title KMT1 family methyltransferases regulate heterochromatin-nuclear periphery tethering via histone and non-histone protein methylation.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA