A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Lamin A delta 150
Type alternative splicing
Species Homo sapiens
Tissue NA
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Analysis of transcript expression during in vitro aging shows that although the levels of lamin A and lamin C transcripts remain unchanged, the lamin A delta 150 transcript increases in late passage cells from HGPS patients and parental controls.
Regulation Gene LMNA
Year 2009
Pubmed ID 19172989
Title Increased expression of the Hutchinson-Gilford progeria syndrome truncated lamin A transcript during cell aging
Drug NA
Disease HGPS
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA