A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Lys36
Type histone modification
Species Caenorhabditis elegans
Tissue C. elegans strain
Experiment Method ChIP;qPCR;ChIP-seq
Up/Down Down
Pro/Anti Anti
Funtion Description In this study, we profiled the genome-wide pattern of trimethylation of Lys36 on histone 3 (H3K36me3) in the somatic cells of young and old Caenorhabditis elegans. We found that genes with dramatic expression change during aging are marked with low or eve
Regulation Gene Lys36
Year 2015
Pubmed ID 25838541
Title Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE62720