A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name macroH2A1
Type histone modification
Species Homo sapiens
Tissue liver
Experiment Method Western blot,PCR
Up/Down differential expression
Pro/Anti NA
Funtion Description macroH2A1 as a novel biomarker of hepatic senescence that could potentially predict prognosis and disease progression.
Regulation Gene macroH2A1
Year 2016
Pubmed ID 26772755
Title DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression.
Drug NA
Disease liver carcinogenesis
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE44970,GSE56588,GSE60753