A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Membrane protein
Type histone modification
Species Homo sapiens
Tissue erythrocyte
Experiment Method ATP Assays ;Density Gradient Separation of Erythrocytes ;Measurement of Pyruvate Kinase Specific Activities ;Sodium Dodecyl Sulfate-Gel Electrophoresis
Up/Down Up
Pro/Anti NA
Funtion Description Of the three major methylated erythrocyte membrane proteins, this increase in carboxyl methylation with age is 4 to 7-fold for bands 2.1 and 3, while the increase in band 4.1 is 3 to 4-fold. This increase in the steady state level of methylation with age
Regulation Gene NA
Year 1983
Pubmed ID 6822497
Title Membrane protein carboxyl methylation increases with human erythrocyte age. Evidence for an increase in the number of methylatable sites
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA