A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MHC
Type histone modification
Species Mus musculus
Tissue muscle
Experiment Method RT-qPCR, Western blot
Up/Down Up
Pro/Anti Anti
Funtion Description Skeletal muscle atrophy is commonly associated with immobilization, ageing, and catabolic diseases such as diabetes and cancer cachexia. Epigenetic regulation of gene expression resulting from chromatin remodeling through histone acetylation has been i
Regulation Gene MuRF1
Year 2015
Pubmed ID 26112243
Title Trichostatin A, a histone deacetylase inhibitor, modulates unloaded-induced skeletal muscle atrophy.
Drug trichostatin A (TSA)
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA