A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Mmp2
Type histone modification
Species Homo sapiens
Tissue blood
Experiment Method qRT-pCR, Western blot, ChIP
Up/Down Down
Pro/Anti Anti
Funtion Description Calorie restriction (CR) is a nonpharmacological intervention that delays the aging process and provides various health benefits. Mechanistically, VSMC-SIRT1-dependent deacetylation of histone H3 lysine 9 on the matrix metallopeptidase 2 (Mmp2) promoter w
Regulation Gene Mmp2
Year 2016
Pubmed ID 27670594
Title Calorie restriction protects against experimental abdominal aortic aneurysms in mice.
Drug 0
Disease Abdominal aortic aneurysm
Environment Factors caloric restriction
Circulating 1
Variant NA
High-throughput NA