| Name |
MOZ
|
| Type |
histone modification
|
| Species |
Mus musculus
|
| Tissue |
embryonic fibroblasts
|
| Experiment Method |
PCR , ChiP, Flow cytometry assay, Western blot, Immunofluorescence
|
| Up/Down |
Up
|
| Pro/Anti |
Anti
|
| Funtion Description |
We show that MOZ is required to maintain normal levels of histone 3 lysine 9 (H3K9) and H3K27 acetylation at the transcriptional start sites of at least four genes, Cdc6, Ezh2, E2f2 and Melk, and normal mRNA levels of these genes.CDC6, EZH2 and E2F2 are k
|
| Regulation Gene |
Cdc6, Ezh2, E2f2, Melk
|
| Year |
2015
|
| Pubmed ID |
25772242
|
| Title |
MOZ (MYST3, KAT6A) inhibits senescence via the INK4A-ARF pathway.
|
| Drug |
0
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|