| Name |
NKG2D
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
atherosclerotic plaques and normal aortas
|
| Experiment Method |
Immunohistochemical staining,Immunofluorescence,Flow cytometry,Western blot,Chromatin immunoprecipitation (ChIP) assay
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
Sirt6 is a member of the class III histone deacetylase family which is associated with aging and longevity. Sirt6 deficient mice show an aging-like phenotype, while male transgenic mice of Sirt6 show increased longevity. Sirt6 acts as a tumor suppressor a
|
| Regulation Gene |
NKG2D
|
| Year |
2016
|
| Pubmed ID |
27045575
|
| Title |
Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice.
|
| Drug |
NA
|
| Disease |
atherosclerosis
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|