| Name |
Nqo1
|
| Type |
histone modification
|
| Species |
Mus musculus
|
| Tissue |
mouse embryo fibroblasts (MEFs)
|
| Experiment Method |
RT-PCR, ChiP, Flow cytometry assay, Western blot, Immunofluorescence
|
| Up/Down |
Up
|
| Pro/Anti |
Anti
|
| Funtion Description |
The histone H3 demethylase Ndy1/KDM2B protects cells from replicative senescence. Changes in the metabolism of reactive oxygen species (ROS) are important for establishing senescence, suggesting that Ndy1 may play a role in redox regulation. At least two
|
| Regulation Gene |
Ndy1
|
| Year |
2008
|
| Pubmed ID |
18838535
|
| Title |
The JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stress.
|
| Drug |
H2O2
|
| Disease |
NA
|
| Environment Factors |
oxidation
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|