| Name |
p21
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
colorectal
|
| Experiment Method |
Western blot, ChIP-quantitative polymerase chain reaction, HDAC activity detection
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
These data suggested that TLBZT induces cell senescence in LS174T cells through a mechanism involving p21 upregulation via histone H3 and H4 acetylation.
|
| Regulation Gene |
p21
|
| Year |
2017
|
| Pubmed ID |
28572741
|
| Title |
Teng-Long-Bu-Zhong-Tang induces p21-dependent cell senescence in colorectal carcinoma LS174T cells via histone acetylation.
|
| Drug |
Teng-Long-Bu-Zhong-Tang (TLBZT)
|
| Disease |
colorectal cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|